Gareth Ainsworth’s side beat MK Dons 2-1 on aggregate over two legs in the semi-finals and had gone on a 13-match unbeaten run before losing 1-0 at Stadium MK.
The Chairboys started the season playing with a back three but have switched to a 4-2-3-1 formation in recent weeks.
To find out more we caught up with Wycombe reporter James Richings from Bucks Free Press to get his predicted line-up for the match.
Here’s who is expected to start for The Chairboys:
. HIGH WYCOMBE, ENGLAND - MAY 05: Sam Vokes of Wycombe Wanderers celebrates with teammates after scoring their sides second goal during the Sky Bet League One Play-Off Semi Final 1st Leg match between Wycombe Wanderers and Milton Keynes Dons at Adams Park on May 05, 2022 in High Wycombe, England. (Photo by Clive Rose/Getty Images)
Wycombe striker Sam Vokes celebrates after scoring against MK Dons. Photo: Clive Rose
. GK: David Stockdale
The 36-year-old kept 18 clean sheets during the regular League One season, the joint highest along with Plymouth's Michael Cooper, and conceded just once in Wycombes' two play-off games against MK Dons. Photo: Michael Steele
. RB: Jason McCarthy
After a few games out of the side earlier in the season, the 26-year-old has started Wycombe's last 15 matches, which included a 13-match unbeaten run. Photo: Ross Kinnaird
5. CM: Josh Scowen
Sunderland fans may be surprised to see Scowen performing so well in the centre of Wycombe's midfield. The 29-year-old was released by the Black Cats last summer but has been one of the first names on the team sheet at Adams Park. Photo: Alex Burstow
6. CM: Dominic Gape
An injury to Curtis Thompson has allowed 27-year-old Gape to partner Scowen in Wycombe's midfield. Gape has started the Chairboys’ last six matches after making just two starts in the first half of the campaign. Photo: Clive Rose
7. RW: Garath McCleary
At 34, McCleary remains a key player for the Chairboys. The wideman has contributed with 11 goals and seven assists in 44 League One appearances this season. Photo: Marc Atkins
8. CAM: Daryl Horgan
Wycombe have a few options when it comes to attacking midfielders, with the likes of Sullay Kaikai and Lewis Wing available, yet Horgan has got the nod in recent weeks. Photo: Alex Burstow