Wycombe are just four points behind the Black Cats ahead of the match having played the same number of matches.
Following back-to-back wins, Sunderland’s preparations have been disrupted after multiple Covid-19 cases.
As a result, Sunderland have recalled Jack Diamond, Josh Hawkes and Anthony Patterson so they can fulfil the fixture and name a matchday squad.
Wycombe usually play with a back three and wing-backs, meaning Sunderland are likely to match them up.
The Black Cats claimed a 3-1 win when the sides met at the Stadium of Light back in August, courtesy of a Ross Stewart brace and Elliot Embleton strike.
Here’s the Sunderland side which could start this weekend:
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9. CAM: Elliot Embleton
Following a spell out of the side, the playmaker has started consecutive games, impressing against Doncaster and Sheffield Wednesday. Photo: JPI Media
10. CAM: Alex Pritchard
The playmaker recorded another assist against Sheffield Wednesday last time out and has arguably been Sunderland's best player in recent weeks. Photo: JPI Media
11. ST: Ross Stewart
A hat-trick against Sheffield Wednesday took the striker's tally to 15 goals this season. Photo: JPI Media