The match at Turf Moor has been brought forward to be played on Friday, March 31 after being selected for TV broadcast.
It means that some players will be flying back to the UK just a few days before the fixture.
"It's very difficult during these breaks to work on the team for the next game, especially as we are playing Burnley on the Friday night,” said Sunderland boss Tony Mowbray. “Three or four of them won't be back until Wednesday afternoon and so we'll have a day to work as a team, and some of these players will have had a couple of games abroad.
Here are the players from both sides who will be away on international duty and their upcoming fixtures:
17. Arijanet Muric (Burnley) - Kosovo
Saturday, March 25 vs Israel (5pm kick-off UK time) - Location: Tel Aviv, Israel | Tuesday, March 28 vs Andorra (7:45pm kick-off UK time) - Location: Prishtina, Kosovo Photo: Ashley Allen
18. Connor Roberts (Burnley) - Wales
Saturday, March 25 vs Croatia (7:45pm kick-off UK time) - Location: Split, Croatia | Tuesday, March 28 vs Latvia (7:45pm kick-off UK time) - Location: Cardiff, Wales Photo: Cameron Smith
19. Anass Zaroury (Burnley) - Morocco
Saturday, March 25 vs Brazil (10pm kick-off UK time) - Location: Tanger, Morocco | Tuesday, March 28 vs Peru (10:30pm kick-off) - Location: Madrid, Spain Photo: Cameron Smith
20. Jewison Bennette (Sunderland) - Costa Rica
Saturday, March 26 vs Martinique (11pm kick-off UK time) - Location: Fort-de-France, Martinique | Wednesday, March 29 vs Panama (3am kick-off UK time) - Location: San Jose, Costa Rica Photo: Frank Reid