Harrison Sonha put the hosts ahead in the 14th minute when he capitalised on a defensive error.
Yet two goals from Wolves forward Chem Campbell gave the visitors all three points in the Premier League 2, Division 2, clash.
The Black Cats handed starts to Benji Kimpioka and Arbenit Xhemajli, who were both part of the first-team squad against Portsmouth on Saturday.
Here’s how each SAFC player fared:
A message from the Football Clubs Editor
Our aim is to provide you with the best, most up-to-date and most informative Sunderland AFC coverage 365 days a year .
This depth of coverage costs, so to help us maintain the high-quality reporting that you are used to, please consider taking out a subscription to our new sports-only package here.
Your support is much appreciated. Richard Mennear, Football Clubs Editor
1 / 4