But which team will Lee Johnson select for the clash against the Fratton Park club?
Here, we take a look ahead of the game on Wearside this coming weekend.
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Is this the team you would pick? Let us know your thoughts on our social media channels.
5. LB: Dennis Cirkin
The left-back has returned to Lee Johnson's tea recently after injury ruled him out for several months.
Photo: COPYRIGHT (C) FRANK REID 20187
6. CM: Corry Evans
Like Wright, Evans adds experience and know-how to Sunderland's inexperienced team.
Photo: FRANK REID 2021
7. CM: Dan Neil
Dan Neil is one of Sunderland's top performers this year.
Photo: COPYRIGHT (C) FRANK REID 20187
8. LW: Elliot Embleton
The attacking midfielder could be set for a stint on the left-hand side of Lee Johnson's attack.
Photo: NEP 2021