Villa boss Dean Smith today confirmed the 25-year-old England international will sit out the St James’ Park visit, having been missing since February 13 with a shin injury.
“Jack Grealish is a lot better, but you won’t see him at Newcastle unfortunately,” said Smith.
"It hasn’t helped that he’s been ill this week, which has kept him off for a couple of days.”
Villa will however welcome back defender Matt Cash as well as attacker Anwar El Ghazi.
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The news of the Villa blow comes on the back of some positive injury updates given by United boss Steve Bruce.
While the Magpies will be without key frontline trio Callum Wilson, Miguel Almiron and Allan Saint-Maximin for tomorrow night’s encounter, Bruce says he is hoping Tottenham Hotspur (H) on April 3 could see them return.
Javier Manquillo and Federico Fernandez have been declared fully fit for tomorrow evening.