It happened on the northbound side of the road at Hylton Bridge in the city.
The incident has caused tailbacks towards the A690 at Doxford Park.
The North East Live traffic account tweeted: "Two vehicle RTC on the A19 northbound in the offside lane at Hylton Bridge #Sunderland.
Sunderland at Wembley: London pub landlord thanks SAFC fans for ‘bumper weekend’ after League play-off final victory over Wycombe Wanderers
Sunderland AFC fans launch fundraiser as ‘thank you’ to staff at Covent Garden pub after Wembley play-off final win
Woman caught drink-driving in Sunderland Aldi car park
Sunderland to get its first roller rink in Keel Square with live DJ - here's when it opens
19 Sunderland locations hosting Queen's Platinum Jubilee street parties
"There are tailbacks towards the A690."