The city's voters were 61% in favour of leaving the EU, with 82,394 opting to part company with the Union.
After spotting the results from Sunderland, Lohan, who appears to be a Remain supporter, tweeted: "Where's Sunderland? Does Sarah Palin live there? Lol"
Twitter users then filled her in on the geography.
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In response to a tweet from The Independent reporting on a drop in the pound after the Sunderland result, she said: "Prove the UK will not trigger anger by allowing (Sunderland) to lower the UK pound."
We're not entirely sure what any of this means, but that's what she had to say, anyway. We hope you feel enlightened as a result.