At its heart is the former Vaux site, now home to new landmark buildings such as City Hall, Maker & Faber and The Beam.
But, it once lay empty for years after the closure of the brewery in 1999.
Supermarket giant Tesco bought the 26-acre site in 2001 to trigger a decade of legal wrangling over its future use.
It was eventually purchased in 2011 by Sunderland City Council with Tesco deciding instead to build a new branch north of the water in Roker Avenue.
We take a look at those ten years and how the site has changed, with photos taken by Echo photographers over the years.
9. The first to arrive
The first building to be completed on the site was The Beam, which opened in 2019 and is now home to businesses including Ocado and North East Screen. | Sunderland Echo
10. Breaking ground
Breaking ground on Sunderland's new City Hall in 2019. From left Sunderland City Council CE Patrick Melia, then Council leader Coun Graeme Miller and Browmer+Kirkland project manager Paul Anderson | Sunderland Echo
11. How it looks today
The site is now home to buildings including office blocks Maker & Faber. | Sunderland Echo