Sunderland have several injury doubts ahead of the trip to Arsenal with George Honeyman, Victor Anichebe and Jason Denayer all struggling to be involved.
Boss David Moyes has also confirmed he has doubts over other players too ahead of the trip to the Emirates Stadium on Tuesday night.
It could mean some of the younger players being involved in the matchday squad, with Joel Asoro, Josh Maja and Elliot Embleton all in contention even though the Under-23s have a huge cup final against Porto at the Stadium of Light on Wednesday.
Honeyman is struggling with a back injury after Lamine Kone fell on top of him in training ahead of the Swansea City game, while Anichebe and Denayer both went off with knocks in the first half.
Speaking at his pre-match press conference, Moyes, when asked whether Honeyman, Anichebe or Denayer would feature, said: "At the moment I wouldn’t think so.
"I’m more concerned that I’ve now got others who are saying they’re injured as well, but we will go there and be committed.
"It might be that we have to take the kids with us to Arsenal but that’s not a problem.
"George Honeyman, Donald Love and Lynden Gooch are all young enough to play in the Under-23 final, and then the next group is Maja, Asoro and Embleton.
"If we have to take them to Arsenal and use them we will do but obviously we'd like to keep them for the game on Wednesday night.
"It might be that we have to take the kids with us to Arsenal but that’s not a problem."
Meanwhile, there are several Sunderland players out of contract this summer including skipper John O'Shea, Seb Larsson, Steven Pienaar, Victor Anichebe and Jan Kirchhoff.
Moyes, who indicated last week he would look to keep hold of one or two, was asked about the latest situation at this morning's press conference.
Talks have taken place with the players with chief executive Martin Bain now overseeing it.
Moyes added: "We’ve spoken to everyone at the club who has a situation with their contracts where it could be terminated or they could leave.
"They all know and they’re ongoing so it’s been passed over to [chief executive] Martin Bain, and they’ll speak with their agents and see where we go."
Sunderland head into the Arsenal game on the back of the disappointing 2-0 defeat to Swansea City at the Stadium of Light, with supporters again turning on the Sunderland boss.
Moyes said the result was bitterly disappointing, coming on the back of the win over Hull City the weekend before.
"After beating Hull we wanted to end the season well so there’s no doubt that Saturday’s result was disappointing," said Moyes.
“Every game counts as far as I’m concerned and you’re judged in every one, so we have to perform much better against Arsenal."