Former Sunderland loanee Nedum Onuoha is one of four QPR defenders missing for tomorrow's Championship clash.
Onuoha, who remains popular on Wearside after a successful stint at right-back during the 2010/11 season, picked up a hamstring injury in September and is expected to be out for at least another two months.
Former England centre-back Steven Caulker is unavailable as he works his way back to fitness, with Grant Hall and James Perch also missing.
It means Alex Baptiste, who Simon Grayson managed at Blackpool earlier in his careers, is likely to continue at centre-back after signing from Middlesbrough on a free in the summer.
The Hoops are yet to win away from home this season but Ian Holloway believes he has found the formula to turn things around.
He said: “I have had phonecall after phonecall from people who know the game who said how well we played against Fulham. But that doesn’t make me feel any better to be honest!
“We have manged two from five games so far and that’s pretty criminal considering how we have played, but we can’t blame anyone else. It’s down to us.
“We have got ourselves in front in a lot of those games – Sheffield Wednesday, Cardiff, Middlesbrough – but we haven’t shut the games down.
“We are looking at doing something else this weekend, a slight tweak. I believe it will work.
“What we have to do is build confidence.
“When you miss the chances you’re creating, it puts a lot more pressure on your backline," he added.
“Everyone needs to work on their finishing - even our goalkeeper went forward and headed wide! So I’ve spoken to the lot of them about taking their chances in front of goal.
“In all seriousness, the midfield need to add a few goals. When you haven’t got a 20-goal-a-season striker, you’ve got to spread them around the team.
“At the minute we’re getting in but not taking our chances. I’m sure that will come.”
The Black Cats are yet to win at home in 2017 but Hollway has warned his side that Grayson's team will present a difficult challenge.
"Sunderland have been struggling at home but we know it is still a tough place to go to,” Holloway said.
“Simon Grayson is a fantastic manager, always very combative.
“But what we need to do is go there and assert ourselves and feel confident about what we can do.”