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While the Black Cats will need to secure a result in order to progress, Phil Parkinson is set to rotate his squad once again and hand opportunities to a number of fringe players and youngsters. But who could benefit? Scroll down and click through the pages to see who could be in contention at Glanford Park:
1. Anthony Patterson
The stopper impressed in the under-23s defeat to Liverpool on Sunday and, with Lee Burge’s fitness still in doubt and Jon McLaughlin set to jet-off on international duty, Patterson could be handed an opportunity to shine. Photo: Frank Reid
2. Bali Mumba
Regular first-team opportunities have eluded Mumba this term, but he’s been a regular for Elliott Dickman’s second string - with the youngster having been deployed as a right-back. This clash could prove the perfect opportunity for him to return to the first-team fold and show Phil Parkinson why he has been so highly-regarded in recent years. Photo: FRANK REID
3. Ruben Sammut
The ex-Chelsea midfielder caught the eye of Jack Ross in pre-season - but can he now impresses his successor? While options in midfield are rife, Sammut could well have the chance to shine from the bench at Glanford Park. Photo: Frank Reid
4. Dylan McGeouch
McGeouch’s only appearance under Parkinson so far has come in this competition, and he is likely in line to be handed another start at Scunthorpe. He’ll be hoping to make a bigger impression this time around. Photo: FRANK REID