Murton New Hesledon had no answer to the firepower of New Seaham Westlea in their George Ivey Memorial Cup first leg tie.
Brennan Yuill, Alex Hutchinson, Sheik Hussain and sub Glen Francis steered Westlea home.
Tom Williams (2), Sean Ryder and Graham Hornsby set up a commanding 4-0 first-leg lead for Easington Leather Cap against Peterlee Central Club.
Steven Freeman, Michael Coates and Stan Stopfph guided Peterlee Hearts home 3-1 against Acre Rigg Celtic, with Scott Jackson replying.
Lee Wood’s goal was enough for Wingate Grange to carry a 1-0 lead into the second leg after a tight battle with Sherburn United.
Hetton Lyons won 4-2 at Haswell Oddfellows Arms, whose marksmen were Robert Lewis and Liam Walker.
Horden CW Supporters Club are in a good position going into their Premier Division Cup quarter-final second leg, following a 5-2 win at Easington Lane WMC.
James Connor’s hat-trick did the damage, with Jack Pounder and Martin Fowler also scoring. Jordan Garside and Barry Robinson replied for Lane.
Horden had Rob Mawson handed a straight red card.
Murton Colliery and Dawdon Welfare Park finished all square at 2-2. Stephen Turner struck twice for Murton, with Marc Ruddick scoring both for Dawdon.
Andy Upperton starred for Murton.
Peterlee Catholic Club take a single goal lead into their second leg, after beating Easington Colliery Club Mechanics.
Liam Wintrip (2) and Bradley Beeston secured a 3-2 win, with Michael Stuart and Nathan Graham replying.
Peterlee Helford United lost 3-2 to Easington Welfare. Gary Shaw notched a brace for Helford, with two-goal Joe Taboun and Curtis Whittle guided Welfare home.
Michael Cockburn starred for Helford.
Stephen Bentley and sub Shaun Bentley struck for Horden Cricket Club, but they lost 4-2 to Seaham The George in their Cyril Dunn Cup quarter-final first leg.
Substitute Jordan Bunts fired a hat-trick to inspire George, supported by a strike from Michael Wilson. Horden had Lee Cleary sent off, with Jamie Wright their top performer.
Easington Southside carry a comfortable five-goal advantage into their second leg after a 7-2 success against Seaham Parkside.
Two goals apiece from Martin Dunn and Stuart Softley, along with efforts from Neil Sargeant, Matt Billyard and sub Connor Burrell, did the damage.
Sean Kavanagh and Kevin Price hit Parkside’s reply.
Easington CIU came out on top 4-2 against Seaham Marlborough, with Rob Huntley’s brace supported by efforts from Jay Harwood and sub Sam White.
Thomas Hobkirk and Ryan Martin struck for Marlborough, whose top performer was John Dale.
Joe Coulson’s hat-trick and an effort from Nathan Grainger saw Wingate Howden defeat Trimdon Royal Oaks 4-2.
Niall Salmon and Adam Setterfield hit Royal Oaks’ consolations.