Brandon United sprang the shock result of the night when they thumped in-form Billingham Synthonia 5-1 in the second round of the Cameron Brewery Brooks Mileson Memorial Cup.
The Teessiders, who have climbed to third-top in the Ebac Northern League Second Division following a string of successes, looked to be on their way to another victory when David Hillerby fired them into a 27th-minute lead.
But Brandon roared back and five goals flowed from Dean Thexton (2), James Ellis (2) and Vinny Gash.
Stokesley SC, who prop up Division Two, crashed to an 11-0 defeat at Shildon, who revelled in six goals from Billy Greulich Smith. Mark Doninger (2), Danny Moore, John Brackstone and Ben Wood also netted.
Stokesley were complimented by onlookers for keeping up the fight throughout the 90 minutes. They did not indulge in time-wasting and committed very few fouls.
In contrast to the goal-fest at Dean Street, only one was scored at Norton and Stockton Ancients, where Liam Thear’s strike proved sufficient for Dunston UTS.
Ben Sayer, Michael Chilton and Jordan Fry eased Morpeth Town home 3-2 against Consett, who were always in with a chance following goals by Ryan King and Michael Sweet.
Guisborough Town plundered five goals in the first hour, courtesy of Danny Earl, Jonathan Helm, Jordan Galloway, Alex White (own goal) and Jordan Towers.
Paul Chow hit a consolation hat-trick in the last 17 minutes for visitors Jarrow Roofing.
North Shields needed extra time before defeating Willington 2-1 at Hall Lane. A 77th-minute own goal by Lewis Milner looked as if it might be enough for the Robins, but, two minutes from time, Anthony Lee levelled.
Willington had Paul Nicholson sent off in extra time and Shields grabbed the winner with a superb strike from Peter Glen-Ravenhill.
Extra time was also played at Esh Winning, who defeated Billingham Town 4-3.
Dan Maloney struck for the Teessiders after just eight minutes and, following Nathan Graham’s 52nd-minute equaliser, four goals were scored in the last six minutes of normal time.
Taylor Hughes made it 2-1 to Esh, but Town then went 3-2 ahead courtesy of a brace from Craig Hutchinson and, right at the death, Adam Smith levelled at 3-3.
Esh took the tie with Liam Clarke’s strike on 98 minutes. Three minutes from the end, Billingham captain Andrew Lambert was sent off.