The Great North Air Ambulance has been called in after a driver became trapped following a crash.
Northumbria Police were called to Tunstall Hope Road, which links Leechmere Road with Ryhope, at 3.40pm today after the crash was reported to its officers.
The North East Ambulance Service said it called at 3.35pm and has sent two of its Hazard Area Response Teams (Hart) and called in the Great North Air Ambulance's helicopter after the person inside became trapped.
In an update, it said a woman was taken to Sunderland Royal Hospital by road after she suffered pain in her back, legs and hip.
Police say the road has now fully reopened and thanked people for their patience and understanding
Earlier today, a force spokesman said: "At this time the eastbound junction with Leechmere Road and the westbound junction with Tunstall Village Green are closed.
"Please avoid the area wherever possible."