Sunderland explosion: How the drama unfolded - in pictures
The blast happened at about 8.50am today in Rosslyn Avenue, Ryhope.
The woman's semi-detached home was flattened, and the house next door badly damaged.
Experts are still investigating the cause of the explosion.
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Hide AdNorthumbria officers along with North East Ambulance Service, Great North Air Ambulance and Tyne & Wear Fire Brigade attended the scene.
A 30-metre cordon remains in place, with the road closed, and people are being asked to avoid the area.
Police say one woman has been taken to the Royal Victoria Infirmary in Newcastle by air ambulance.
She has suffered burns, and her condition is described as serious but stable.
All other residents affected are now safe and have been accounted for.
The former library on Black Road has been opened for evacuated residents.