The collision took place on the Queen Alexandra Bridge shortly after 2.30pm.
No injuries were reported.
A Northumbria Police spokesman said: “At about 2.43pm this afternoon, police received a report of a two-vehicle road traffic collision near the Queen Alexandra Bridge, in Sunderland.
“Officers attended the scene.
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"Nobody was injured and the road is now clear.”
North East Live Traffic posted on Twitter: "Two vehicle RTC on the A1231 westbound on the northern side of the QA Bridge Sunderland involving a car and a bus."