The Prime Minister will first meet with his most senior Cabinet colleagues and hear expert recommendations on the review and the next phase of his road map on Monday.
He will then consult his Cabinet on Tuesday and outline the plans to Parliament for pubs, restaurants, hotels and hairdressers.
Guidance will be published for each sector on how businesses can reduce the spread of Covid-19 when they reopen.
And the public are expected to be warned that the newest relaxation of rules will be the first to be reversed if there are widespread breaches that prompt the virus to spread uncontrollably.
These are the top rated GP practices in and around Sunderland as rated by patients
The 12 areas in and around Sunderland with the lowest Covid case rates as infections continue to rapidly fall
Ratings for dentists in and around Sunderland, as ranked by NHS reviews
These are Sunderland's 15 best GP practices - as rated by patients
The 12 areas in and around Sunderland with the lowest Covid case rates as infections continue to fall in May
A No 10 spokesman said: "The reason we are able to move forward this week is because the vast majority of people have taken steps to contain the virus.
"The more we open up, the more important it is that everyone follows the social-distancing rules.
"We will not hesitate to put the handbrake on to stop the virus running out of control."