Sunderland duo Jordan Pickford and Duncan Watmore have been called up to the England Under-21 squad
The England Under-21 squad face Kazakhstan on Thursday 6 October and Bosnia & Herzegovina on Tuesday 11 October in the Under-21 Euro qualifiers.
Marcus Rashford looks certain to be in Gareth Southgate's first England squad after he was left out of the under-21s forthcoming double header.
Southampton's Nathan Redmond had also been tipped for a possible call-up by Gareth Southgate but he will remain with the Young Lions for now.
He was named in a 22-man squad that will travel to Kazakhstan on October 6 and host Bosnia & Herzegovina in Walsall five days later, with a point in the former enough to book a spot at Euro 2017 in Poland.
Aidy Boothroyd takes charge of the team, promoted from the under-20s to cover Southgate's secondment.
Bristol City's on-loan Chelsea striker Tammy Abraham, who has scored 10 goals in 13 games for the Robins this term, is in line to win his first cap.
Brendon Galloway, Mason Holgate, Isaac Hayden and Derby County goalkeeper Jonathan Mitchell, from Hartlepool, and Newcastle United stopper Freddie Woodman are the other uncapped names in Aidy Boothroyd's squad.