Sunderland West End are looking to make progress in the Total Sport Alan Hood Charity Cup after seeing their Durham Trophy ambitions dashed on penalties last week.
Manager Barry Cook takes his men south to Wolviston looking to clinch a semi-final place.
West End have a full squad to choose from, as well as the addition of Kevin Humble, recently signed from Ashbrooke Belford House.
Manager Cook said: “I am looking forward to pushing on from last week’s disappointing exit from the Durham Trophy.”
Wolviston have midfielder Michael Rainsley and defender Karl Barry, who both missed last week’s Durham Trophy exit at Hall Farm Glasshus, back in the squad.
Striker Nathan Bayes is out injured, while fellow frontman Nathan Mohun is a doubt, following a knock last week.
The other quarter-final tie sees Boldon CA travelling to Cleator Moor Celtic.
Boldon secretary Kevin Oliver said: “We still have an injury problem with captain Jack Lawton, who’s still out. Jonny Gage, who is acting captain, is available after a slight knock on his hamstring.”
James Pickering is available after missing the last home game, but Phil Gray is missing due to work commitments.
Oliver added: “We’ve only played Cleator Moor Celtic once. We delivered a good game but got beat. It’s always hard to travel away to Cumbria, and we’re expecting a hard game.”
Ashbrooke Belford House have John Coomber set to make his debut in tomorrow’s league trip to bottom club Harton & Westoe.
Jack Murphy, Greg Bradley, Shaun Fisk, Dan Lowson and Mason Burton all return to the squad, while late fitness tests will be given to club captain Nathan Burrell and Dale Wells.
Belford must look to arrest a dismal away record, with just one win and seven defeats on the road in the league so far.
Harton will be without the suspended Brodie Simpson and Jack Burrell (broken toe), while long-term absentees Shaun Edwards and Danny Lydon are in light training but are unlikely to feature yet.
Brian Farries and Shaun Heads will have fitness tests on muscle injuries, but both are expected to be in contention.
The experienced trio of Paul Trosh, Sean Frazer and David Graham are back, along with defender Duncan O’Brien and midfielder Ricky Brown
Silksworth CW entertain Redcar Athletic in an intriguing battle of fourth v third.
Silksworth secretary David Steele said: “James Cook is sadly unavailable due to serving the last of three games of suspension. Davey Clarke is also suspended after reaching five bookings.
“David Stevens is also out injured this weekend, but Liam Gill and Brandon Alderson are included in the squad having missed out last week due to being cup-tied.”
Redcar are set to retain Peter Passman at centre-half, while teenager Joshua Cooper is poised to stay at right-back, giving Chris Bivens a more attacking role.
Redcar hope David Abel and Luke Woodall are available, allowing Michael Woodhouse to revert to his normal midfield spot.
Seaham Red Star Reserves travel to Hartlepool, with Jordan Thompson and David Baker returning after being unavailable last weekend.
Jonathan Hodgson should start after a short injury lay-off, but work commitments rule out influential skipper Mark Ruddock. Goalkeeper Shay Adamson will look to build on a fine performance last week.
Pool should have Cameron Gordon returning, but they must wait on a check for Sam Cook, who missed out with injury last Saturday.
Leam Rangers will hope to beat lowly visitors Darlington 1883 Reserves at Hilltop, while leaders Jarrow face the long trip west to Windscale.
Josh Allen, Callum Smith, Peter Kane, Micky Turnbull, Bri Johnson and Max Kirkham all miss out, while Kai Elliott is rated doubtful. Keeper Gary Frater returns.
Jarrow boss Dave Bell said: “We are hoping Darren Morton and Jonny Hirst get over their injuries.
“It is always a difficult game at Windscale and this is where, with so many missing, we need our squad to pull us through. I am absolutely confident that with the character and desire of the lads we have in our squad that this is what we will do.
“What has been a consistent attribute this season is our hard work and we need to keep that going again this weekend. We were pleased with our result last week to get back to winning ways and we are determined to keep that going this weekend. But we do know that we need to be well prepared for this game as it will be really difficult.”
Coxhoe Athletic must do without David Gibson, Ross Morrow, Chris Baxter and Scott Young when they entertain South Shields Reserves in the TWR Shipowners’ Charity Cup.
Kyle Morris, Mitchell McKenna and Aidan Hart return to Coxhoe’s squad.
Shields Reserves secretary Philip Reay said: “We are looking to bounce back from a disappointing defeat against Seaham last weekend. One of our players was sent off, but we’re hoping to have a full squad for this cup match.
“The only doubt is Ewan Simpson, who picked up a knock, but had treatment in midweek, so hopefully he’ll be available. Tristan Mitford and Nathan Sinclair are still out with long -term injuries.”
Prudhoe Town visit Stokesley SC in the Monkwearmouth Cup.