The A19 northbound was closed after an accident this morning.
A Renault Laguna overturned at the north end of the Hylton Viaduct around 10am and the road was closed while recovery was under way.
Two people suffered minor injuries. No other vehicles were involved.
Traffic was diverted over the A1231 entry and exit slip roads.
The clean-up operation was complete and the road reopened by lunchtime.