Tony Mowbray’s side were beaten 1-0 by Cardiff last time out, following a run of three consecutive wins.
Sunderland have been without several first-team players in recent weeks, with Pierre Ekwah, Dennis Cirkin and Bradley Dack among the players who have been sidelined.
Here’s our predicted Black Cats line-up to face Sheffield Wednesday:
1. GK: Anthony Patterson
The Sunderland keeper was unfortunate to lose his clean sheet in the closing stages against Cardiff as Sunderland conceded from a late set-piece. Photo: Frank Reid
2. RB: Trai Hume
Hume has started every league game for Sunderland this season and often stepped into a midfield position from right-back. Photo: Frank Reid
3. CB: Luke O’Nien
O’Nien has performed well at centre-back alongside Ballard this season but appeared to lose Cardiff defender Mark McGuinness for The Bluebirds’ late winner. Photo: Frank Reid
4. CB: Dan Ballard
Ballard produced another strong performance against Cardiff as the visitors often went direct to forward Ike Ugbo. Photo: Frank Reid